Brain-Computer Interface to Deliver Individualized Multisensory Intervention for Neuropathic Pain.

ABSTRACT: To unravel the complexity of the neuropathic pain experience, researchers have tried to identify reliable pain signatures (biomarkers) using electroencephalography (EEG) and skin conductance (SC). Nevertheless, their use as a clinical aid to design personalized therapies remains scarce and patients are prescribed with common and inefficient painkillers. To address this need, novel non-pharmacological interventions, such as transcutaneous electrical nerve stimulation (TENS) to activate peripheral pain relief via neuromodulation and virtual reality (VR) to modulate patients' attention, have emerged. However, all present treatments suffer from the inherent bias of the patient's self-reported pain intensity, depending on their predisposition and tolerance, together with unspecific, pre-defined

SUBMITTER: Aurucci GV 

PROVIDER: S-EPMC10480109 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature