Combining glucose and high-sensitivity cardiac troponin in the early diagnosis of acute myocardial infarction.

ABSTRACT: Glucose is a universally available inexpensive biomarker, which is increased as part of the physiological stress response to acute myocardial infarction (AMI) and may therefore help in its early diagnosis. To test this hypothesis, glucose, high-sensitivity cardiac troponin (hs-cTn) T, and hs-cTnI were measured in consecutive patients presenting with acute chest discomfort to the emergency department (ED) and enrolled in a large international diagnostic study (NCT00470587). Two independent cardiologists centrally adjudicated the final diagnosis using all clinical data, including serial hs-cTnT measurements, cardiac imaging and clinical follow-up. The primary diagnostic endpoint was index non-ST-segment elevation MI (NSTEMI). Prognostic endpoints were all-cause death, and cardiovascular (CV)

SUBMITTER: Yufera-Sanchez A 

PROVIDER: S-EPMC10480296 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature