Comparison of balanced and unbalanced crystalloids as resuscitation fluid in patients treated for cardiogenic shock.

ABSTRACT:

Background

The efficacy and safety of saline versus balanced crystalloid solutions in ICU-patients remains complicated by exceptionally heterogenous study population in past comparative studies. This study sought to compare saline and balanced crystalloids for fluid resuscitation in patients with cardiogenic shock with or without out-of-hospital cardiac arrest (OHCA).

Methods

We retrospectively analyzed 1032 propensity score matched patients with cardiogenic shock from the Munich University Hospital from 2010 to 2022. In 2018, default resuscitation fluid was changed from 0.9% saline to balanced crystalloids. The primary endpoint was defined as 30-day mortality rate.

Results

Patients in the saline group (n = 516) had a similar 30-day mortality rate as patients treated

SUBMITTER: Gmeiner J 

PROVIDER: S-EPMC10481512 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature