Prognostic implications of left ventricular ejection fraction trajectory changes in heart failure

ABSTRACT:

Aims

The latest guidelines recommended to assess the trajectory of left ventricular ejection fraction (LVEF) in patients with heart failure (HF). However, there is limited data on the trajectory of LVEF in real-world settings. In this study, we investigated the frequency and prognostic implications of changes in LVEF trajectory.

Methods

Patients were divided into intensified LVEF, static LVEF, and worsening LVEF groups based on the transitions of HF types from baseline to follow-up. The intensified and worsening LVEF groups were further subdivided into mild (≤10% absolute changes of LVEF) and significant (>10% absolute changes of LVEF) increase or decrease groups according to the magnitude of change. The incidences and associations of changes in LVEF with patient outcomes

SUBMITTER: Ding Z 

PROVIDER: S-EPMC10481864 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature