Association of the gut microbiota with clinical variables in obese and lean Emirati subjects.

ABSTRACT:

Background

Growing evidence supports the role of gut microbiota in obesity, yet exact associations remain largely unknown. Specifically, very little is known about this association in the Emirati population.

Methods

We explored differences in gut microbiota composition, particularly the Firmicutes/Bacteroidetes (F/B) ratio, between 43 obese and 31 lean adult Emirate counterparts, and its association with obesity markers, by using V3-V4 regions of 16 S ribosomal RNA gene sequencing data. Furthermore, we collected anthropometric and biochemical data.

Results

The two major phyla in obese and lean groups were Firmicutes and Bacteroidetes. We observed a significantly lower alpha diversity (Shannon index) in obese subjects and a significant difference in beta diversity and

SUBMITTER: Ahmad MA 

PROVIDER: S-EPMC10481963 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature