Systematic review and meta-analysis of segmentectomy vs. lobectomy for stage IA non-small cell lung cancer.

ABSTRACT:

Background

Whether segmentectomy is appropriate for stage IA non-small cell lung cancer (NSCLC), especially for stage IA NSCLC with a tumor size of 2-3 cm, remains controversial. Thus, we conducted this meta-analysis to compare segmentectomy and lobectomy for stage IA NSCLC with a tumor size of 2-3 cm and IA ≤2 cm NSCLC.

Methods

A systematic screening of online databases (PubMed, Embase, Web of Science, and Cochrane Library) was conducted regarding the terms of perioperative outcomes, overall survival (OS), recurrence-free survival (RFS), and disease-free survival (DFS). The inverse-variance and Mantel-Haenszel approaches were used to pool effect sizes for survival outcomes and perioperative outcomes.

Results

A total of 10 articles were included in the analysis. The p

SUBMITTER: Dai Z 

PROVIDER: S-EPMC10482631 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature