Evaluation of automated sample preparation system for lymph node sampling.

ABSTRACT:

Background

Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-FNA) has revolutionized the diagnostic and staging approach to non-small cell carcinoma and thoracic lymphadenopathy. However, obstacles to efficacy of rapid on-site evaluation (ROSE) of the samples include variability in sample quality and slow and cumbersome process in the procedure room leading to extended procedure time. The purpose of this pilot study was to evaluate the feasibility and specimen quality of lymph node biopsies prepared through a novel automated system for automated fixation, drying and staining compared to standard slide preparation method.

Methods

We performed a prospective, single-center pilot feasibility study of patients undergoing EBUS. Samples were split into con

SUBMITTER: Duke JD 

PROVIDER: S-EPMC10482632 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature