LC-HRMS method for study of pharmaceutical uptake in plants: effect of pH under aeroponic condition.

ABSTRACT: Global climate changes cause water scarcity in many regions, and the sustainable use of recycled water appears crucial, especially in agriculture. However, potentially hazardous compounds such as pharmaceuticals can enter the food chain and pose severe risks. This paper aims to study the presence of selected pharmaceutical active compounds (PhACs) and their metabolites in crops grown in aeroponic conditions and evaluate the potential of PhAC plant uptake. A solvent extraction with an acidified mixture of acetonitrile and water followed by LC-HRMS was developed and validated for quantifying nine pharmaceuticals and their nine metabolites in three plants. We aimed for a robust method with a wide linear range because an extensive concentration range in different matrices was expected. The dev

SUBMITTER: Svecova H 

PROVIDER: S-EPMC10482775 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature