A randomized controlled trial comparing femtosecond-enabled deep anterior lamellar keratoplasty and standard deep anterior lamellar keratoplasty (FEDS Study).

ABSTRACT:

Objectives

To compare outcomes of femtosecond-enabled deep anterior lamellar keratoplasty (FE-DALK) and standard deep anterior lamellar keratoplasty (S-DALK).

Methods

An open label, randomized controlled trial (Kensington Eye Institute, Toronto, ON, Canada) including 100 eyes of 97 participants with either keratoconus or corneal scarring, randomized to either FE-DALK (n = 48) or S-DALK (n = 49).

Primary outcomes

postoperative astigmatism and surgically induced corneal astigmatism (SIA) - both at 15 months.

Secondary outcomes

6-, 12- and 15-month postoperative uncorrected- and best spectacle-corrected visual acuity, steep and flat keratometry, manifest sphere and astigmatism, rate of conversion to penetrating keratoplasty (PK), big-bubble success, central cornea

SUBMITTER: Sorkin N 

PROVIDER: S-EPMC10482827 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature