Waist-hip ratio is superior to BMI in predicting liver-related outcomes and synergizes with harmful alcohol use.

ABSTRACT:

Background

Obesity is associated with liver disease, but the best obesity-related predictor remains undefined. Controversy exists regarding possible synergism between obesity and alcohol use for liver-related outcomes (LRO). We assessed the predictive performance for LROs, and synergism with alcohol use, of abdominal obesity (waist-hip ratio, WHR), and compared it to overall obesity (body mass index, BMI).

Methods

Forty-thousand nine-hundred twenty-two adults attending the Finnish health-examination surveys, FINRISK 1992-2012 and Health 2000 studies, were followed through linkage with electronic healthcare registries for LROs (hospitalizations, cancers, and deaths). Predictive performance of obesity measures (WHR, waist circumference [WC], and BMI) were assessed by Fine-Gray

SUBMITTER: Aberg F 

PROVIDER: S-EPMC10482890 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature