Choroidal vascularity index in hereditary optic neuropathies.

ABSTRACT:

Purpose

To assess the choroidal vascularity index (CVI) in patients affected by Leber hereditary optic neuropathy (LHON) compared to patients affected by dominant optic atrophy (DOA) and healthy subjects.

Methods

In this retrospective study, we considered three cohorts: LHON eyes (48), DOA eyes (48) and healthy subjects' eyes (48). All patients underwent a complete ophthalmologic examination, including best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) acquisition. OCT parameters as subfoveal choroidal thickness (Sub-F ChT), mean choroidal thickness (ChT), total choroidal area (TCA), luminal choroidal area (LCA) were calculated. CVI was obtained as the ratio of LCA and TCA.

Results

Subfoveal ChT in LHON patients did not show statistically signi

SUBMITTER: Battista M 

PROVIDER: S-EPMC10482917 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature