Relationship between clinical parameters and quality of life in primary Sjogren's Syndrome: a prospective study.

ABSTRACT:

Objectives

To quantify the impact of dry eye disease (DED) on health and vision related quality of life (HR-QOL, VR-QOL) in patients with Primary Sjögren's Syndrome (pSS).

Methods

Thirty-four participants with a confirmed diagnosis of pSS as per the 2016 ACR EULAR criteria participated. Main outcome measures included ocular surface parameters and HR-QOL and VR-QOL questionnaires. Clinical examination included visual acuity, Schirmer I testing, ocular surface staining (OSS) and measurement of tear film breakup time. The questionnaires included Ocular Surface Disease Index, National Eye Institute Visual Function Questionnaire-25, Short Form-36 (SF-36) and EULAR Sjogren's Syndrome Patient Reported Index.

Results

Despite the majority of participants (28 female, 6 male, me

SUBMITTER: Greenan E 

PROVIDER: S-EPMC10482965 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature