Vitamin K Intake and Risk of Lung Cancer: The Japan Collaborative Cohort Study.

ABSTRACT:

Background

Limited reports from prospective human studies investigated the possible role of vitamin K in the development of lung cancer although vitamin K's anticarcinogenic activities were verified from several in vitro and in vivo studies. We investigated the associations between total vitamin K intake from food and the development of lung cancer based on this large prospective cohort study.

Methods

A validated food frequency questionnaire was used to examine vitamin K intake among 42,166 (16,341 men and 25,825 women) at the Japan Collaborative Cohort Study's baseline (1988-1990). Hazard ratios (HRs) and 95% confidence intervals (CIs) of incident lung cancer were calculated using the Cox proportional hazard regression method based on vitamin K consumption quartiles.

Res

SUBMITTER: Yan F 

PROVIDER: S-EPMC10483107 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature