Intrawound Vancomycin Powder Application for Preventing Surgical Site Infection Following Cranioplasty.

ABSTRACT:

Objective

Surgical site infection is the most detrimental complication following cranioplasty. In other surgical fields, intrawound vancomycin powder application has been introduced to prevent surgical site infection and is widely used based on results in multiple studies. This study evaluated the effect of intrawound vancomycin powder in cranioplasty compared with the conventional method without topical antibiotics.

Methods

This retrospective study included 580 patients with skull defects who underwent cranioplasty between August 1, 1998 and December 31, 2021. The conventional method was used in 475 (81.9%; conventional group) and vancomycin powder (1 g) was applied on the dura mater and bone flap in 105 patients (18.1%; vancomycin powder group). Surgical site infection was

SUBMITTER: Youn SB 

PROVIDER: S-EPMC10483168 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature