Phenotypic and genotypic characterization of Neisseria gonorrhoeae isolates from Yaounde, Cameroon, 2019 to 2020.

ABSTRACT: This study investigated antimicrobial resistance (AMR) phenotypes and genotypes exhibited by Neisseria gonorrhoeae from Yaoundé, Cameroon. AMR to tetracycline, penicillin and ciprofloxacin was observed although none of the isolates had reduced susceptibility to azithromycin, cefixime or ceftriaxone. Whole genome sequence (WGS) data were obtained and, using a threshold of 300 or fewer locus differences in the N. gonorrhoeae core gene multilocus sequence typing (cgMLST) scheme, four distinct core genome lineages were identified. Publicly available WGS data from 1355 gonococci belonging to these four lineages were retrieved from the PubMLST database, allowing the Cameroonian isolates to be examined in the context of existing data and compared with related gonococci. Examination

SUBMITTER: Tayimetha CY 

PROVIDER: S-EPMC10483411 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature