Neural Signatures of Predictive Strategies Track Individuals Along the Autism-Schizophrenia Continuum.

ABSTRACT:

Background and hypothesis

Humans develop a constellation of different representations of the external environment, even in the face of the same sensory exposure. According to the Bayesian framework, these differentiations could be grounded in a different weight assigned to prior knowledge vs. new external inputs in predictive inference. Since recent advances in computational psychiatry suggest that autism (ASD) and schizophrenia (SSD) lie on the two diametric poles of the same predictive continuum, the adoption of a specific inferential style could be routed by dispositional factors related to autistic and schizotypal traits. However, no studies have directly investigated the role of ASD-SSD dimension in shaping the neuro-behavioral markers underlying perceptual inference.

Study

SUBMITTER: Tarasi L 

PROVIDER: S-EPMC10483460 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature