Sexual and drug use risk behaviour trajectories among people treated for recent HCV infection: the REACT study.

ABSTRACT:

Introduction

Exploration of sexual and drug use behaviours following treatment for recent hepatitis C virus (HCV) is limited. This analysis modelled behavioural trajectories following treatment for recent HCV and assessed reinfection.

Methods

Participants treated for recent HCV in an international trial (enrolled 2017-2019) were followed at 3-monthly intervals for up to 2 years to assess longitudinal behaviours. Population-averaged changes were assessed using generalized estimating equations. Distinct behavioural trajectories were identified using group-based trajectory modelling. HCV reinfection incidence was calculated using person-years (PY) of observation.

Results

During the follow-up of 212 participants (84% gay and bisexual men [GBM]; 69% HIV; 26% current inject

SUBMITTER: Carson JM 

PROVIDER: S-EPMC10483502 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature