The risk of acute kidney injury in colorectal cancer survivors: an english population-based matched cohort study.

ABSTRACT:

Background

Colorectal cancer survival has improved in recent decades but there are concerns that survivors may develop kidney problems due to adverse effects of cancer treatment or complications of the cancer itself. We quantified the risk of acute kidney injury (AKI) in colorectal cancer survivors compared to people with no prior cancer.

Methods

Retrospective matched cohort study using electronic health record primary care data from the Clinical Practice Research Datalink GOLD linked to hospital data in England (HES-APC). Individuals with colorectal cancer between 1997-2018 were individually matched on age, sex, and GP practice to people with no prior cancer. We used Cox models to estimate hazard ratios for an incident hospital diagnosis of AKI in colorectal cancer survivor

SUBMITTER: Andresen K 

PROVIDER: S-EPMC10483792 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature