Exposure to Fine Particulate Matter Constituents and Human Semen Quality Decline: A Multicenter Study.

ABSTRACT: Exposure to fine particulate matter (PM < 2.5 μm in diameter [PM_2.5]) may accelerate human sperm quality decline, although research on this association is limited. Our objective was to investigate the relationship between exposure to the chemical constituents of PM_2.5 air pollution and decreased sperm quality and to further explore the exposure-response relationship. We conducted a multicenter population-based cohort study including 78,952 semen samples from 33,234 donors at 6 provincial human sperm banks (covering central, northern, southern, eastern, and southwestern parts of China) between 2014 and 2020. Daily exposure to PM_2.5 chemical composition was estimated using a deep learning model integrating a density ground-based measure network at a 1 km reso

SUBMITTER: Wang L 

PROVIDER: S-EPMC10483896 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature