First detection of Varicella Zoster Virus clade 9 cases in India during mpox surveillance.

ABSTRACT:

Background

The multi-country mpox outbreak across the globe has led to the systematic surveillance of mpox cases in India. During the surveillance of mpox, we encountered cases of Varicella Zoster Virus (VZV) in suspected mpox cases amongst children & adults. This study focused on the genomic characterization of VZV in India.

Methods

A total of 331 mpox suspected cases were tested for VZV through real-time PCR, and the positive samples were subjected to next-generation sequencing to retrieve the whole genome of VZV using CLC genomics software. Phylogenetic analysis has been done in MEGA 11.0 software to identify circulating clades.

Result

Of the 331 suspected cases, 28 cases with vesicular rashes were found to be positive for VZV. The maximum genome could be retrieved

SUBMITTER: Kumar A 

PROVIDER: S-EPMC10484040 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature