Efficacy of different surgical treatments for management of anal fistula: a network meta-analysis.

ABSTRACT:

Purpose

Currently, the anal fistula treatment which optimises healing and preserves bowel continence remains unclear. The aim of our study was to compare the relative efficacy of different surgical treatments for AF through a network meta-analysis.

Methods

Systematic searches of MEDLINE, EMBASE and CENTRAL databases up to October 2022 identified randomised controlled trials (RCTs) comparing surgical treatments for anal fistulae. Fistulae were classified as simple (inter-sphincteric or low trans-sphincteric fistulae crossing less than 30% of the external anal sphincter (EAS)) and complex (high trans-sphincteric fistulae involving more than 30% of the EAS). Treatments evaluated in only one trial were excluded from the primary analyses to minimise bias. The primary outcomes wer

SUBMITTER: Bhat S 

PROVIDER: S-EPMC10485107 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature