Association of gut microbiota composition and craniosynostosis.

ABSTRACT:

Background

Gut microbiota has been reported to be associated with a series of metabolic diseases including metabolic bone disease. However, study about gut microbiota and craniosynostosis (CS) is very rare. We aim to investigate the gut microbiota composition in CS patients and assess the possible relationship.

Methods

A total of 30 infants with CS and 30 infants with non-CS treated in Children's Hospital of Nanjing Medical University of Jiangsu Province from June 2021 to March 2022 were finally included in this study. All processing and analysis are carried out using 16S ribosomal RNA (rRNA) high-throughput gene sequencing.

Results

The CS group have significantly lower levels of family, genus, and species than non-CS group (all P<0.05). Furthermore, Staphylococcal

SUBMITTER: Fu Z 

PROVIDER: S-EPMC10485648 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature