Survival and quality-of-life outcomes in early-stage NSCLC patients: a literature review of real-world evidence.

ABSTRACT:

Aim

Assess the long-term survival and quality-of-life outcomes in early-stage NSCLC (eNSCLC) patients.

Methods

Review of long-term survival and quality-of-life after curative treatment in eNSCLC patients in observational studies.

Results

Disease-free proportion decreased in stage III vs stage I patients. Recurrence-free proportion decreased with age and disease stage. Advanced stage and vascular invasion increased risk of late recurrence. Conditional 5-year relative survival rates did not exceed 87%, indicating higher mortality in eNSCLC survivors. Lower conditional survival rates and relative survival rates were associated with older age and advanced disease. Survivors of eNSCLC had poorer physical quality-of-life.

Conclusion

Despite curative-intent therapy, s

SUBMITTER: Jovanoski N 

PROVIDER: S-EPMC10485735 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature