Calcium Channel Blocker Use and Associated Glaucoma and Related Traits Among UK Biobank Participants.

ABSTRACT:

Importance

Calcium channel blocker (CCB) use has been associated with an increased risk of glaucoma in exploratory studies.

Objective

To examine the association of systemic CCB use with glaucoma and related traits among UK Biobank participants.

Design, setting, and participants

This population-based cross-sectional study included UK Biobank participants with complete data (2006-2010) for analysis of glaucoma status, intraocular pressure (IOP), and optical coherence tomography (OCT)-derived inner retinal layer thicknesses. Data analysis was conducted in January 2023.

Exposure

Calcium channel blocker use was assessed in a baseline touchscreen questionnaire and confirmed during an interview led by a trained nurse.

Main outcomes and measures

The primary outc

SUBMITTER: Kastner A 

PROVIDER: S-EPMC10485742 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature