Is a Single Nephrographic Phase Computed Tomography Sufficient for Detecting Urothelial Carcinoma in Patients with Visible Haematuria? A Prospective Paired Noninferiority Comparison.

ABSTRACT:

Background

There is uncertainty about the utility of multiphase computed tomography (CT) compared with single-phase CT in the routine examination of patients with visible haematuria (VH).

Objective

To compare the accuracies of single nephrographic phase (NP) CT and four-phase CT in detecting urothelial carcinoma (UC).

Design setting and participants

This was a single-centre, prospective, paired, noninferiority study of patients with painless VH referred for CT before cystoscopy between September 2019 and June 2021. Patients were followed up for 1 yr to ascertain UC diagnosis.

Intervention

All patients underwent four-phase CT (control), from which single NP CT (experimental) was extracted. Both were independently assessed for UC.

Outcome measurements and stat

SUBMITTER: Galtung KF 

PROVIDER: S-EPMC10485786 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature