Disease evolution in systemic juvenile idiopathic arthritis: an international, observational cohort study through JIRcohort.

ABSTRACT:

Background

Systemic juvenile idiopathic arthritis (systemic JIA) is a severe disease with both systemic and joint inflammation. This study aims to identify predictors of disease evolution within the systemic JIA population enrolled in the Juvenile Inflammatory Rheumatism cohort (JIRcohort).

Methods

Observational patient cohort study with 201 recruited children from 4 countries (3 European, 1 North Africa) from 2005 until 2019, using retrospectively (2005-2015) and prospectively (2015-2019) routine care collected data.

Results

Sixty-five patients with complete follow-up data for 24 months after first diagnosis were classified as monophasic (n = 23), polyphasic (n = 6) or persistent group (n = 36) corresponding to their evolution (unique flare, recurrent flares, or pers

SUBMITTER: Wallimann M 

PROVIDER: S-EPMC10485973 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature