Cognitive outcomes in patients treated with neuromuscular electrical stimulation after coronary artery bypass grafting.

ABSTRACT:

Objective

Mechanisms of neurocognitive injury as post-operative sequelae of coronary artery bypass grafting (CABG) are not understood. The systemic inflammatory response to surgical stress causes skeletal muscle impairment, and this is also worsened by immobility. Since evidence supports a link between muscle vitality and neuroprotection, there is a need to understand the mechanisms by which promotion of muscle activity counteracts the deleterious effects of surgery on long-term cognition.

Methods

We performed a clinical trial to test the hypothesis that adding neuromuscular electrical stimulation (NMES) to standard rehabilitation care in post-CABG patients promotes the maintenance of skeletal muscle strength and the expression of circulating neuroprotective myokines.

Res

SUBMITTER: Lo Re V 

PROVIDER: S-EPMC10486105 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature