Functional characterization of fungal lytic polysaccharide monooxygenases for cellulose surface oxidation.

ABSTRACT:

Background

Microbial lytic polysaccharide monooxygenases (LPMOs) cleave diverse biomass polysaccharides, including cellulose and hemicelluloses, by initial oxidation at C1 or C4 of glycan chains. Within the Carbohydrate-Active Enzymes (CAZy) classification, Auxiliary Activity Family 9 (AA9) comprises the first and largest group of fungal LPMOs, which are often also found in tandem with non-catalytic carbohydrate-binding modules (CBMs). LPMOs originally attracted attention for their ability to potentiate complete biomass deconstruction to monosaccharides. More recently, LPMOs have been applied for selective surface modification of insoluble cellulose and chitin.

Results

To further explore the catalytic diversity of AA9 LPMOs, over 17,000 sequences were extracted from public d

SUBMITTER: Mathieu Y 

PROVIDER: S-EPMC10486138 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature