Methylation-related genes involved in renal carcinoma progression.

ABSTRACT: Renal carcinomas are a group of malignant tumors often originating in the cells lining the small tubes in the kidney responsible for filtering waste from the blood and urine production. Kidney tumors arise from the uncontrolled growth of cells in the kidneys and are responsible for a large share of global cancer-related morbidity and mortality. Understanding the molecular mechanisms driving renal carcinoma progression results crucial for the development of targeted therapies leading to an improvement of patient outcomes. Epigenetic mechanisms such as DNA methylation are known factors underlying the development of several cancer types. There is solid experimental evidence of relevant biological functions modulated by methylation-related genes, associated with the progression of different ca

SUBMITTER: Zamora-Fuentes JM 

PROVIDER: S-EPMC10486271 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature