Transcriptomic and proteomic studies of condylar ossification of the temporomandibular joint in porcine embryos.

ABSTRACT:

Background

The ossification mechanism of the temporomandibular joint (TMJ) condyle remains unclear in human embryo. The size and structure of TMJ, shape of articular disc and the characteristics of omnivorous chewing in the pig are similar to those of humans. The pig is an ideal animal for studying the mechanism of ossification of the TMJ condyle during the embryonic period.

Method

In a previous study by our group, it was found that there was no condylar ossification on embryonic day(E) 45, but the ossification of condyle occurred between E75 and E90. In this study, a total of 12 miniature pig embryos on E45 and E85 were used. Six embryos were used for tissue sections (3 in each group). The remaining six embryos were used for transcriptomic and proteomic studies to find diff

SUBMITTER: Xiang L 

PROVIDER: S-EPMC10486337 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature