Low Gluten Beers Contain Variable Gluten and Immunogenic Epitope Content.

ABSTRACT: Gluten content labels inform food choice and people practicing a gluten-free diet rely upon them to avoid illness. The regulations differ between jurisdictions, especially concerning fermented foodstuffs such as beer. Gluten abundance is typically measured using ELISAs, which have come into question when testing fermented or hydrolysed foodstuffs such as beer. Mass spectrometry can be used to directly identify gluten peptides and reveal false negatives recorded by ELISA. In this survey of gluten in control and gluten-free beers, gluten protein fragments that contain known immunogenic epitopes were detected using liquid chromatography-mass spectrometry in multiple beers that claim to be gluten-free and have sufficiently low gluten content, as measured by ELISA, to qualify as being gluten-fr

SUBMITTER: Nye-Wood MG 

PROVIDER: S-EPMC10486350 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature