Transcriptomic Response of Differentiating Porcine Myotubes to Thermal Stress and Donor Piglet Age.

ABSTRACT: Climate change is a current concern that directly and indirectly affects agriculture, especially the livestock sector. Neonatal piglets have a limited thermoregulatory capacity and are particularly stressed by ambient temperatures outside their optimal physiological range, which has a major impact on their survival rate. In this study, we focused on the effects of thermal stress (35 °C, 39 °C, and 41 °C compared to 37 °C) on differentiating myotubes derived from the satellite cells of Musculus rhomboideus, isolated from two different developmental stages of thermolabile 5-day-old (p5) and thermostable 20-day-old piglets (p20). Analysis revealed statistically significant differential expression genes (DEGs) between the different cultivation temperatures, with a higher number of genes

SUBMITTER: Sarais F 

PROVIDER: S-EPMC10487455 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature