Efficient Reductions of Dimethylhydrazones using Preformed Primary Amine Boranes.

ABSTRACT: A convenient method for the reduction of N,N-dimethylhydrazones using amine borane complexes generated in situ is described. It was found that primary amine borane complexes performed exceedingly well at reducing N,N-dimethylhydrazones in as little as 1.1 equivalents, furnishing the corresponding air-sensitive hydrazine products in excellent yields.

SUBMITTER: Frabitore C 

PROVIDER: S-EPMC10488297 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature