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Renal Denervation as a Complementary Treatment Option for Uncontrolled Arterial Hypertension: A Situation Assessment.


ABSTRACT: Uncontrolled arterial hypertension is a major global health issue. Catheter-based renal denervation has shown to lower blood pressure in sham-controlled trials and represents a device-based, complementary treatment option for hypertension. In this situation assessment, the authors, who are practicing experts in hypertension, nephrology, general practice and cardiology in the Republic of Ireland, discuss the current evidence base for the BP-lowering efficacy and safety of catheter-based renal denervation with different modalities. Although important questions remain regarding the identification of responders, and long-term efficacy and safety of the intervention, renal denervation has the potential to provide much-needed help to address hypertension and its adverse consequences. The therapeutic approach needs to be multidisciplinary and personalised to take into account the perspective of patients and healthcare professionals in a shared decision-making process.

SUBMITTER: Wagener M 

PROVIDER: S-EPMC10488551 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature

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Renal Denervation as a Complementary Treatment Option for Uncontrolled Arterial Hypertension: A Situation Assessment.

Wagener Max M   Dolan Eamon E   Arnous Samer S   Galvin Joseph J   Murphy Andrew W AW   Casserly Ivan I   Eustace Joseph J   O'Connor Stephen S   McCreery Charles C   Shand James J   Wall Catherine C   Matiullah Saijad S   Sharif Faisal F  

Journal of clinical medicine 20230829 17


Uncontrolled arterial hypertension is a major global health issue. Catheter-based renal denervation has shown to lower blood pressure in sham-controlled trials and represents a device-based, complementary treatment option for hypertension. In this situation assessment, the authors, who are practicing experts in hypertension, nephrology, general practice and cardiology in the Republic of Ireland, discuss the current evidence base for the BP-lowering efficacy and safety of catheter-based renal den  ...[more]

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