Depression and HIV: a scoping review in search of neuroimmune biomarkers.

ABSTRACT: People with HIV are at increased risk for depression, though the neurobiological mechanisms underlying this are unclear. In the last decade, there has been a substantial rise in interest in the contribution of (neuro)inflammation to depression, coupled with rapid advancements in the resolution and sensitivity of biomarker assays such as Luminex, single molecular array and newly developed positron emission tomography radioligands. Numerous pre-clinical and clinical studies have recently leveraged these next-generation immunoassays to identify biomarkers that may be associated with HIV and depression (separately), though few studies have explored these biomarkers in co-occurring HIV and depression. Using a systematic search, we detected 33 publications involving a cumulative N = 10 59

SUBMITTER: Mudra Rakshasa-Loots A 

PROVIDER: S-EPMC10489482 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature