SCP Viz - A universal graphical user interface for single protein analysis in single cell proteomics datasets.

ABSTRACT: Single cell proteomics (SCP) requires the analysis of dozens to thousands of single human cells to draw biological conclusions. However, assessing of the abundance of single proteins in output data presents a considerable challenge, and no simple universal solutions currently exist. To address this, we developed SCP Viz, a statistical package with a graphical user interface that can handle small and large scale SCP output from any instrument or data processing software. In this software, the abundance of individual proteins can be plotted in a variety of ways, using either unadjusted or normalized outputs. These outputs can also be transformed or imputed within the software. SCP Viz offers a variety of plotting options which can help identify significantly altered proteins between groups,

SUBMITTER: Warshanna A 

PROVIDER: S-EPMC10491148 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature