Geo-environmental factors and the effectiveness of mulberry leaf extract in managing malaria.

ABSTRACT: Malaria prevalence has become medically important and a socioeconomic impediment for the endemic regions, including Purulia, West Bengal. Geo-environmental variables, humidity, altitude, and land use patterns are responsible for malaria. For surveillance of the endemic nature of Purulia's blocks, statistical and spatiotemporal factors analysis have been done here. Also, a novel approach for the Pf malaria treatment using methanolic leaf extract of Morus alba S1 has significantly reduced the parasite load. The EC₅₀ value (1.852) of the methanolic extract of M. alba S1 with P. falciparum 3D7 strain is close to the EC₅₀ value (0.998) of the standard drug chloroquine with the same chloroquine-sensitive strain. Further studies with an in-silico model have shown successful

SUBMITTER: Pradhan S 

PROVIDER: S-EPMC10491663 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature