Association of lipid metabolism with pneumonia risk in under-five children in China.

ABSTRACT:

Objective

The relationship between lipid metabolism and pneumonia in under-five children remains unclear. The aim of the study was to explore the association of several lipids, lipoproteins and apolipoproteins with the risk of childhood pneumonia, and to initially reveal the mechanisms involved.

Methods

There were 1000 children with confirmed severe pneumonia and 1000 healthy controls (18-59 months old) in the study. Serum levels of several lipids, lipoproteins and apolipoproteins were measured. The occurrence of hypoxaemia and serum level of C-reactive protein were recorded. Multivariate logistic regression and spearman correlation analysis were adopted to assess the correlation between these variables to achieve the research objective.

Results

First, higher triglyce

SUBMITTER: Wang Q 

PROVIDER: S-EPMC10492140 | biostudies-literature | 2023 Sep-Oct

REPOSITORIES: biostudies-literature