Gut microbiome profile of Chinese hypertension patients with and without type 2 diabetes mellitus.

ABSTRACT:

Background

The coexistence of hypertension and type 2 diabetes mellitus (T2DM) may largely increase the risk for cardiovascular disease. However, there is no clear consensus on the association between hypertension and the risk of diabetes. Gut microbiota plays important roles in the development of hypertension and T2DM, but whether there is difference between hypertension patients with or without T2DM has not been explored yet.

Methods

We recruited 101 hypertension patients in this study (72 patients without T2DM named HT group and 29 patients with T2DM named HT-T2DM group). Their blood samples were collected for testing clinical characteristics and fecal samples were tested for bacterial DNA using 16 S ribosomal RNA gene sequencing targeting the V3 and V4 region. The data o

SUBMITTER: Ding H 

PROVIDER: S-EPMC10492291 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature