Maternal COVID-19 causing intrauterine foetal demise with microthrombotic placental insufficiency: a case report.

ABSTRACT:

Background

Pregnant women have an increased risk of getting infected with SARS-CoV-2 and are more prone to severe illness. Data on foetal demise in affected pregnancies and its underlying aetiology is scarce and pathomechanisms remain largely unclear.

Case

Herein we present the case of a pregnant woman with COVID-19 and intrauterine foetal demise. She had no previous obstetric or gynaecological history, and presented with mild symptoms at 34 + 3 weeks and no signs of foetal distress. At 35 + 6 weeks intrauterine foetal death was diagnosed. In the placental histopathology evaluation, we found inter- and perivillous fibrin depositions including viral particles in areas of degraded placental anatomy without presence of viral entry receptors and SARS-CoV-2 infection of the place

SUBMITTER: Nonn O 

PROVIDER: S-EPMC10492311 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature