Coffee consumption and periodontitis: a Mendelian Randomization study.

ABSTRACT:

Background

Coffee is one of the most consumed beverages in the world, coffee consumption has been growing in the United States over the past 20 years. Periodontitis is defined by the pathologic loss of the periodontal ligament and destruction of the connective tissue attachment and alveolar bone loss and is related to different systemic diseases and conditions. However, the causality has remained unclarified, thus we regarded discovering the causal relationship between coffee consumption and the liability to periodontitis as the objective of the study.

Methods

Coffee consumption was subdivided into binary coffee consumption and continuous coffee consumption to refine the study design. Genetic instruments were stretched from the MRC-IEU's (MRC Integrative Epidemiology Unit) o

SUBMITTER: Liao WZ 

PROVIDER: S-EPMC10492363 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature