Biomarkers for diagnosis of stage III, grade C with molar incisor pattern periodontitis in children and young adults: a systematic review and meta-analysis.

ABSTRACT:

Aim

To explore the existing salivary, gingival crevicular fluid (GCF), blood, and serum biomarkers associated with grade C molar-incisor pattern (C/MIP) periodontitis in systemically healthy children and young adults.

Materials and methods

Cross-sectional, case-control, and cohort studies on stage III grade C periodontitis or former equivalent diagnosis with analysis of molecular biomarkers in saliva, GCF, blood, or serum were retrieved from six databases and screened based on the eligibility criteria. The risk of bias in included studies was evaluated. Meta-analysis was planned for biomarkers assessed using the same detection methods and sample type in at least two papers.

Results

Out of 5621 studies identified at initial screening, 28 papers were included in the qua

SUBMITTER: Alamri MM 

PROVIDER: S-EPMC10492694 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature