Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-de-Diego C
PROVIDER: S-EPMC10492845 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Sanchez-de-Diego Cristina C Virumbrales-Muñoz María M Hermes Brock B Juang Terry D TD Juang Duane S DS Riendeau Jeremiah J Guzman Emmanuel Contreras EC Reed-McBain Catherine A CA Abizanda-Campo Sara S Patel Janmesh J Hess Nicholas J NJ Skala Melissa C MC Beebe David J DJ Ayuso Jose M JM
Communications biology 20230909 1
Biological tissues are highly organized structures where spatial-temporal gradients (e.g., nutrients, hypoxia, cytokines) modulate multiple physiological and pathological processes including inflammation, tissue regeneration, embryogenesis, and cancer progression. Current in vitro technologies struggle to capture the complexity of these transient microenvironmental gradients, do not provide dynamic control over the gradient profile, are complex and poorly suited for high throughput applications. ...[more]