Effects of mandibular advancement devices on upper airway dimensions in obstructive sleep apnea: responders versus non-responders.

ABSTRACT:

Study objectives

To compare the effects of mandibular advancement device (MAD) therapy on upper airway dimensions between responders and non-responders with mild to moderate obstructive sleep apnea (OSA).

Methods

Thirty-one participants (21 men and 10 women) with a mean ± SD apnea-hypopnea index (AHI) of 16.6 ± 6.7 events/h, and aged 48.5 ± 13.9 years, were included in this study. Polysomnographic recordings and cone beam computed tomography (CBCT) scans in supine position were performed for every participant at baseline and at 3-month follow-up with their MAD in situ. Responders were defined as having ≥ 50% reduction in baseline AHI with a residual AHI < 10 events/h. The primary outcome variable was the minimal cross-sectional area of the upper airway (CSAmin).

Results</

SUBMITTER: Shi X 

PROVIDER: S-EPMC10492877 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature