Rapid quantitative analysis and suspect screening of per-and polyfluorinated alkyl substances (PFASs) in aqueous film-forming foams (AFFFs) and municipal wastewater samples by Nano-ESI-HRMS.

ABSTRACT: A rapid analytical method for per- and polyfluoroalkyl substances (PFASs) combining nano-electrospray ionization and high-resolution mass spectrometry (Nano-ESI-HRMS) was developed and applied to aqueous film-forming foams (AFFFs) and wastewater samples collected from three local wastewater treatment plants (WWTPs). This method exhibited high sensitivity with lower limits of detection (LODs) of 3.2∼36.2 ng/L for 22 target PFAS analytes. In AFFF formulations, Nano-ESI-HRMS enabled the first-time detection of trifluoromethanesulfonic acid (TFMS), perfluoroethyl cyclohexanesulfonate (PFECHS), 6:2 fluorotelomer sulfonyl amido sulfonic acid (6:2 FTSAS-SO₂), N-ammoniopropyl perfluoroalkanesulfonamidopropylsulfonate (N-AmP-FASAPS, n = 3-6), ketone-perfluorooctanesulfonic acid (Keto-PFO

SUBMITTER: Wu C 

PROVIDER: S-EPMC10492922 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature