State of Shock: Contemporary Vasopressor and Inotrope Use in Cardiogenic Shock.

ABSTRACT: Cardiogenic shock is characterized by tissue hypoxia caused by circulatory failure arising from inadequate cardiac output. In addition to treating the pathologic process causing impaired cardiac function, prompt hemodynamic support is essential to reduce the risk of developing multiorgan dysfunction and to preserve cellular metabolism. Pharmacologic therapy with the use of vasopressors and inotropes is a key component of this treatment strategy, improving perfusion by increasing cardiac output, altering systemic vascular resistance, or both, while allowing time and hemodynamic stability to treat the underlying disease process implicated in the development of cardiogenic shock. Despite the use of mechanical circulatory support recently garnering significant interest, pharmacologic hemodynam

SUBMITTER: Bloom JE 

PROVIDER: S-EPMC10492962 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature