Predicting sepsis using a combination of clinical information and molecular immune markers sampled in the ambulance.

ABSTRACT: Sepsis is a time dependent condition. Screening tools based on clinical parameters have been shown to increase the identification of sepsis. The aim of current study was to evaluate the additional predictive value of immunological molecular markers to our previously developed prehospital screening tools. This is a prospective cohort study of 551 adult patients with suspected infection in the ambulance setting of Stockholm, Sweden between 2017 and 2018. Initially, 74 molecules and 15 genes related to inflammation were evaluated in a screening cohort of 46 patients with outcome sepsis and 50 patients with outcome infection no sepsis. Next, 12 selected molecules, as potentially synergistic predictors, were evaluated in combination with our previously developed screening tools based on clinica

SUBMITTER: Tuerxun K 

PROVIDER: S-EPMC10493220 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature