Questionnaire PLD-complaint-specific assessment identifies need for therapy in polycystic liver disease: A multi-centric prospective study.

ABSTRACT:

Background and aims

Polycystic liver disease (PLD) can lead to extensive hepatomegaly. Symptom relief is the primary goal of the treatment. The role of the recently developed disease-specific questionnaires for identification of the thresholds and the assessment of therapy needs further investigation.

Methods

A five-year prospective multi-centric observational study in 21 hospitals in Belgium gathered a study population of 198 symptomatic PLD-patients of whom the disease-specific symptom questionnaire PLD-complaint-specific assessment (POLCA) scores were calculated. The thresholds of the POLCA score for the need for volume reduction therapy were analyzed.

Results

The study group consisted of mostly (82.8%) women with baseline mean age of 54.4 years ±11.2, median liver

SUBMITTER: Billiet A 

PROVIDER: S-EPMC10493353 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature