The additive value of CA19.9 monitoring in a pancreatic cyst surveillance program.

ABSTRACT:

Background

Surveillance of pancreatic cysts focuses on the detection of (mostly morphologic) features warranting surgery. European guidelines consider elevated CA19.9 as a relative indication for surgery. We aimed to evaluate the role of CA19.9 monitoring for early detection and management in a cyst surveillance population.

Methods

The PACYFIC-registry is a prospective collaboration that investigates the yield of pancreatic cyst surveillance performed at the discretion of the treating physician. We included participants for whom at least one serum CA19.9 value was determined by a minimum follow-up of 12 months.

Results

Of 1865 PACYFIC participants, 685 met the inclusion criteria for this study (mean age 67 years, SD 10; 61% female). During a median follow-up of 25 mon

SUBMITTER: Levink IJM 

PROVIDER: S-EPMC10493362 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature