Dataset Information

Prevalence of depressive disorder in the adult population of Latin America: a systematic review and meta-analysis.

ABSTRACT:

Background

Depressive disorder is one of the leading causes of disability worldwide; however its prevalence and association with inequality and crime is poorly characterised in Latin America. This study aimed to: i. systematically review population-based studies of prevalence of ICD/DSM depressive disorder in Latin America, ii. report pooled regional, country, and sex-specific prevalence estimates, and iii. test its association with four country-level development indicators: human development (HDI), income (Gini) and gender inequality (GII), and intentional homicide rate (IHR).

Methods

We conducted a systematic review and meta-analysis of population-based studies reporting primary data on the prevalence of ICD/DSM depressive disorder in Latin America from 1990 to 2023, irrespective of language. We searched PubMed, PsycINFO, Cochrane Library, SciELO (regional database), LILAC (regional database), and available grey literature. Study quality was assessed using JBI's critical appraisal tools. We generated pooled estimates using random-effects meta-analysis; heterogeneity was assessed using the I² statistic. Meta-regression analyses were used to test associations of depression prevalence with indicators of inequality and human development. The study was registered with PROSPERO (CRD42019143054).

Findings

Using data from 40 studies in Latin America, lifetime, 12-month, and current prevalence of ICD/DSM depressive disorder were calculated at 12.58% (95% CI 11.00%-14.16%); 5.30% (4.55-6.06%), and 3.12% (2.22-4.03), respectively. Heterogeneity was high across lifetime, 12-month, and current prevalence, sex, and countries. 12-month and current prevalence was associated with higher Gini and GII, 12-month prevalence with lower HDI, and current prevalence with higher IHR.

Interpretation

We found a high prevalence of ICD/DSM depressive disorders in Latin America, and a statistically significant association with inequality and development indicators. The high heterogeneity found across prevalence periods and the major gaps in country representation underscore the need to escalate efforts to improve mental health access and research capabilities in Latin America. Systematic, comparable prevalence estimates would inform more effective decision-making in the region.

Funding

Pfizer Independent Medical Education Grant.

SUBMITTER: Errazuriz A

PROVIDER: S-EPMC10493603 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature

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Publications

Prevalence of depressive disorder in the adult population of Latin America: a systematic review and meta-analysis.

Errazuriz Antonia A Avello-Vega Dalia D Ramirez-Mahaluf Juan P JP Torres Rafael R Crossley Nicolas A NA Undurraga Eduardo A EA Jones Peter B PB

Lancet regional health. Americas 20230906

<h4>Background</h4>Depressive disorder is one of the leading causes of disability worldwide; however its prevalence and association with inequality and crime is poorly characterised in Latin America. This study aimed to: <i>i</i>. systematically review population-based studies of prevalence of ICD/DSM depressive disorder in Latin America, <i>ii</i>. report pooled regional, country, and sex-specific prevalence estimates, and <i>iii</i>. test its association with four country-level development ind ...[more]

PMID: 37701460

Similar Datasets

Project description:IntroductionPrediabetes represents a significant public health challenge in Latin America. Its prevalence varies considerably depending on the diagnostic criteria used, which hinders a precise understanding of its magnitude in the region.ObjectiveTo estimate the prevalence and incidence of prediabetes in Latin America through a systematic review (SR).MethodsA SR and meta-analysis was conducted searching through October 25, 2024 in SCOPUS, EMBASE, Web of Science, and PubMed. Studies were included if they: (1) used probabilistic sampling methods, (2) included adult participants (≥ 18 years), (3) assessed prediabetes using WHO criteria, fasting glucose, postprandial glucose, or HbA1c, and (4) were published in English, Spanish, or Portuguese. Studies using non-probabilistic sampling, focusing on specific medical conditions, or lacking sufficient data to calculate prevalence or incidence were excluded. Random-effect models were used to estimate pooled prevalence, with heterogeneity assessed using I² statistics and publication bias through funnel plots.ResultsTwenty-five studies from 9 countries published between 1992 and 2023 were analyzed. The pooled prevalence of prediabetes was 24% (95% CI: 18-30%). According to specific criteria, the prevalences were: WHO 11% (95% CI: 5-18%), FG 18% (95% CI: 10-27%), PPG 20% (95% CI: 3-46%), and HbA1c 32% (95% CI: 21-52%). High heterogeneity was observed among studies (I² = 99-100%, p < 0.001). Only one study analyzed the incidence, which was 12.8%.ConclusionsPrediabetes prevalence in Latin America is high, with significant variations by diagnostic criteria. The limited number of incidence studies and high heterogeneity highlight the need for standardized approaches in future research. Implementation of preventive strategies and strengthening of epidemiological surveillance systems are crucial for addressing this public health challenge.Supplementary informationThe online version contains supplementary material available at 10.1007/s40200-024-01549-6.

Dataset Information

Prevalence of depressive disorder in the adult population of Latin America: a systematic review and meta-analysis.

Background

Methods

Findings

Interpretation

Funding

Publications

Prevalence of depressive disorder in the adult population of Latin America: a systematic review and meta-analysis.

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